Qualitative and quantitative phytochemical composition, antimicrobial activity, and brine shrimp cytotoxicity of different solvent extracts of Acanthus polystachyus, Keetia gueinzii, and Rhynchosia elegans

Abstract Background The root, root bark, and tubers of Acanthus polystachyus , Keetia gueinzii Rhynchosia elegans are used for managing bacterial fungal infections among the Luo community Kisumu East Sub County in Kenya. However, data on efficacy these plants against common pathogens is not available. safety also known. This study aimed to investigate phytochemical composition, antimicrobial properties, different solvent extracts roots, barks, . broth microdilution method evaluated activities tuber (water, acetone, methanol) Gram-positive ( Bacillus cereus Staphylococcus aureus ), gram-negative Escherichia coli Candida albicans ) microorganisms were evaluation. was Artemia salina composition determined using qualitative quantitative assays. Results In general, displayed poor properties relative conventional agents including Amoxicillin, Gentamicin, Nystatin. aqueous extract aqueous, methanol safe but all other cytotoxic salina. Conclusions These findings suggest that use limited by cytotoxicity.